Biomimetic Materials Science Laboratory
|Staff & Contact|
|Educational Staff||Prof. Jun-ichi Kikuchi
Assistant Prof. Kazuma Yasuhara, Keishiro Tahara
Education and Research Activities in the Laboratory
The Biomimetic Materials Science Laboratory is developing seeds that promise to take a leading role in bio-nano science and information technology through learning from biological systems and developing new molecular materials and systems that exceed the original biological systems.
1. Development of cerasome as a new bio-nano material
We have developed cerasome, a new nanocapsule, by applying a ceramic coating to only a single atomic layer on the surface of an artificial cell membrane, and are exploring its possibility as a bio-nano material (Fig. 1). For example, we utilize the high structure stability of cerasome to establish artificial multicell systems, magnetically manipulate artificial cells, and develop highly efficient gene transfer methods.
2. Development of molecule-based next-generation information and telecommunications systems
Biological systems have wireless, nano-scale information processing systems. Thus, we learn from biological systems how to create artificial cells that incorporate enzymes and receptors and to develop nano-devices that can process information on light, heat, or ions. Furthermore, we are organizing and coordinating these nano-devices organically to develop “molecular communication,” a molecule-based information and communications system for the future (Fig. 2).
3. Production of molecular devices made of fullerene and carbon nano tubes.
We produce fullerene C60 solubilized on an artificial cell membrane and carbon nanotubes made of complex macromolecular or supramolecular compounds (Fig. 3). We use their optical characteristics to study the application of various molecular devices such as cell activated devices, photoelectric conversion elements, and sensors.
Explanatory Pictures of Research Activities
- Fig. 1
- Fig. 2
- Fig. 3
Recent Research Papers and Achievements
1. J. Kikuchi and K. Yasuhara, “Cerasomes: A New Family of Artificial Cell Membranes with Ceramic Surface”, in “Advances in Biomimetics“, A. George, ed., InTech, Rijeka (2011), pp. 231-250
2. M. Mukai, K. Maruo, Y. Sasaki, and J. Kikuchi, “Intermolecular Communication on a Liposomal Membrane. Enzymatic Amplification of a Photonic Signal with Gemini Peptide Lipid as a Membrane-bound Artificial Receptor”, Chem. Eur. J., 18, 3258-3263 (2012)
3. A. Ikeda, M. Mori, K. Kiguchi, K. Yasuhara, J. Kikuchi, K. Nobusawa, M. Akiyama, M. Hashizume, T. Ogawa, and T. Takeya, “Advantages and Potential of Lipid-Membrane-Incorporating Fullerenes Prepared by the Fullerene-Exchange Method”, Chem. Asian J., 7, 605-613 (2012)