NAIST Graduate School of Materials Science

Biomimetic Materials Science Laboratory

Staff & Contact
Educational StaffProf. Jun-ichi Kikuchi
Assistant Prof. Kazuma Yasuhara
ContactTEL: +81-743-72-6099
URLhttp://mswebs.naist.jp/LABs/kikuchi/index-j.html

The Biomimetic Materials Science Laboratory takes a leading role in bionanoscience and information technology by learning from biological systems and developing new molecular materials and systems that exceed their original biological functionality.

1. Development of molecule-based next-generation information and telecommunications systems
Biological systems have built-in wireless, nanoscale information processing systems. From biological systems, we learn how to create artificial cells that incorporate enzymes and receptors, and develop nanodevices that can process information on light, heat, and ions. Furthermore, we are organizing and coordinating these nanodevices organically to develop “molecular communication,” a molecule-based information and communications system for the future. (Fig. 1)

2. Modulation of biological function by triggered membrane dynamics
Membrane dynamics, such as morphological change of the cell membrane and molecular assembly in the cell membrane, are important molecular mechanisms expressing and/or regulating many cellular functions in biological systems. We design and synthesize membrane-active agents, which can induce membrane dynamics and modulate biological functions. (Fig. 2)

3. Development of a basis for molecular computing utilizing redox and supramolecular chemistry
Biological systems effectively utilize weak intermolecular interactions such as hydrogen-bonding and electrostatic interaction. We are developing methodologies to combine these interactions with artificial metal-metal interactions of redox-active compounds to fabricate energy-saving molecular devices and logic gates. (Fig. 3)

  • Fig. 1
  • Fig. 2
  • Fig. 3

1. J. Kikuchi and K. Yasuhara, “Cerasomes: A New Family of Artificial Cell Membranes with Ceramic Surface”, in “Advances in Biomimetics”, A. George, ed., InTech, Rijeka (2011), pp. 231-250
2. K. Yasuhara, T. Kawataki, S. Okuda, S. Oshima and J. Kikuchi, “Spontaneously Formed Semipermeable Organic-Inorganic Hybrid Vesicle Permitting Molecular Weight Selective Transmembrane Passage”, Chem. Commun. 49, 665-667 (2013).
3. K. Tahara, N. Terashita, T. Akita, S. Katao, J. Kikuchi and K. Tokunaga, “Electrochemistry, charge transfer properties, and theoretical investigation of a macrocyclic boronate dimer of 1′,1”’-biferrocenediboronic acid and related ferrocenyl boronate complexes”, Organometallics, 34, 299-308 (2015).

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