Division of Materials Science, NAIST

Sensory Materials and Devices Laboratory (with Shimadzu Corporation)

Staff & Contact
Educational StaffVisiting Prof. Keishi Kitamura, Masaki Kanai
Visiting Associate Prof. Shigeyoshi Horiike
TEL: +81-774-95-1650

We are advancing our research on sensor and device-related fundamental technologies such as microfabrication. We take advantage of these technologies to then conduct research on various devices such as electrophoresis chips, cell culture chips (Fig.1), microreactors, electro-osmotic pumps, and vapor-liquid separation chips. Additionally, we are also furthering research on molecular imaging technology (Fig.2) and X-ray image sensor systems (Fig.3) to be applied in the medical diagnosis field, as well as working on the integration of these technologies to realize highly functional ultra micro chemical analysis systems (μTAS: Micro Total Analysis Systems).

Taking advantage of semiconductor manufacturing process technologies to apply micromachining to silicon and glass substrates of sub-micron dimensions, we develop functional devices with one-micron sized three dimensional structures that are used for chemical analysis and chemical manipulation (reaction or extraction).

We are also active in the medical diagnosis field, focusing on molecular imaging technology and X-ray imaging systems. We pursue the application of molecular imaging-related technologies such as the molecular design of molecular probes or microreactor based synthetic apparatuses, to medical diagnosis fields including cancer detection at its very early stage. X-ray imaging systems are an important technology in the medical diagnosis field and are investigating a large area 2D X-ray detector composed of a poly crystalline CdZnTe film, a thin film transistor array and read out electronics.

Our laboratory research themes include:

1. Microchemical analysis systems

2. Microreactors and micropumps

3. Molecular imaging

4. X-ray photoconductor materials: Poly crystalline growth and evaluation

5. X-ray imaging systems

  • Fig.1 Cell culture chips
  • Fig.2
    A biocompatible polymer gel

A PET detector

1.Y. Ishii et al., “Timing performance simulation of TOF-PET detector using GATE v8.0”, The 65th JSAP Spring Meeting, Tokyo, Japan (2018).
2.Y. Ishii et al., “Timing Resolution of GFAG Scintillators for TOF-PET”, The 78th JSAP Autumn Meeting, Fukuoka, Japan (2017).
3.M. Nakazawa et al., “Development of a 64ch SiPM-based TOF-PET Detector with High Spatial and Timing Resolutions Using Multiplexing Architecture”, IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Atlanta, GA, USA (2017).
4.Y. Ishii et al., “Timing Resolution of GPS Scintillator with Several Ce Concentrations for TOF-PET”, The 64th JSAP Spring Meeting, Kanagawa, Japan (2017).
5.Y Yamakawa et al., “Development of a dual-head mobile DOI-TOF PET system having multi-modality compatibility”, Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Seattle, WA, USA (2014).
6.KK. Miyake et al., “Performance Evaluation of a New Dedicated Breast PET Scanner Using NEMA NU4-2008 Standards”, Journal of Nuclear Medicine 55(7), 1198-203 (2014).
7.Y. Kimura et al., “Novel system using microliter order sample volume for measuring arterial radioactivity concentrations in whole blood and plasma for mouse PET dynamic study”, Physics in Medicine and Biology 58(22), 7889-903 (2013).


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