Division of Materials Science, NAIST

Ms. Jinyu Hao, a 2nd year master course student, of the Biomimetic Molecular Science Laboratory received a student award at the membrane symposium 2019.

Ms. Jinyu Hao, a 2nd year master course student, of the Biomimetic Molecular Science Laboratory received a student award at the membrane symposium 2019, which was held at Osaka University on November 11th and 12th 2019. 17 excellent presentations were awarded among 84 posters.

Spontaneously Formed Lipid Bilayer Nanodisc as a Novel Carrier for Drug Delivery

Jinyu Hao, Yuma Mitsuyoshi, Rapenne Gwénaël, Kazuma Yasuhara

I am greatly honored to receive this award. I would like to express my sincere appreciation to all of my laboratory members especially my supervisors, Yasuhara-sensei and Rapenne-sensei who give me energetic guidance and support. This award encouraged me a lot for my future research.

Drug delivery systems have attracted a lot of attention due to their potential to enhance the efficacy of medicinal drugs with diminishing unexpected side effects. Development of nanocarriers that can efficiently deliver the drugs to a specific target is needed to realize the drug delivery systems. In this study, we developed a membrane-active amphiphilic polymer that spontaneously forms lipid bilayer nanodiscs through the fragmentation of membrane. We examined the interaction of the lipid bilayer nanodiscs with cells to demonstrate their potential as a novel molecular carrier for drug delivery.

 

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