奈良先端科学技術大学院大学 物質創成科学領域

Staff & Contact

Education and Research Activities in the Laboratory

We are advancing our research on sensor and device-related fundamental technologies such as microfabrication. We take advantage of these technologies to then conduct research on various devices such as electrophoresis chips, cell culture chips (Fig.1), microreactors, electro-osmotic pumps, and vapor-liquid separation chips. Additionally, we are furthering research on biomaterial especially for tissue engineering (Fig.2) and Gamma-ray image sensor systems (Fig.3) to be applied in the medical diagnosis field, as well as working on the integration of these technologies to realize highly functional ultra micro chemical analysis systems (μTAS: Micro Total Analysis Systems).

Research Theme

Taking advantage of semiconductor manufacturing process technologies to apply micromachining to silicon and glass substrates of sub-micron dimensions, we develop functional devices with one-micron sized three dimensional structures that are used for chemical analysis and chemical manipulation (reaction or extraction).

We are also active in the medical diagnosis field, focusing on molecular imaging technology and X-ray imaging systems. We pursue the application of molecular imaging-related technologies such as positron emission tomography (PET) to medical diagnosis fields including cancer detection at its earliest stages. X-ray imaging systems are an important technology in the medical diagnosis field and we are investigating a phase contrast imaging system using an X-ray Interferometer.
Our laboratory research themes include:

1. Microchemical analysis systems
2. Microreactors and micropumps
3. Biomaterial for tissue engineering
4. Molecular imaging: Positron emission tomography
5. X-ray imaging systems

Explanatory Pictures of Research Activities

Recent Research Papers and Achievements

1. N. Morimoto et al., “Talbot-Lau interferometry-based x-ray imaging system with retractable and rotatable gratings for nondestructive testing” Review of Scientific Instruments 91(2), 023706 (2020).
2. I. Kabeshita et al., “Effect of Sampling Intervals on TOF Estimation from PET Detector Signals with CNNs”, The 80th JSAP Autumn Meeting, Sapporo, Japan (2019).
3. Y. Ishii et al., “Timing performance simulation of TOF-PET detector using GATE v8.0”, The 65th JSAP Spring Meeting, Tokyo, Japan (2018).
4. Y. Ishii et al., “Timing Resolution of GFAG Scintillators for TOF-PET”, The 78th JSAP Autumn Meeting, Fukuoka, Japan (2017).
5. M. Nakazawa et al., “Development of a 64ch SiPM-based TOF-PET Detector with High Spatial and Timing Resolutions Using Multiplexing Architecture”, IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Atlanta, GA, USA (2017).
6. Y. Ishii et al., “Timing Resolution of GPS Scintillator with Several Ce Concentrations for TOF-PET”, The 64th JSAP Spring Meeting, Kanagawa, Japan (2017).
7. Y. Yamakawa et al., “Development of a dual-head mobile DOI-TOF PET system having multi-modality compatibility”, Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Seattle, WA, USA (2014).