1. Cd²⁺-specific fluorescence response of methoxy-substituted N, N‑bis(2-quinolylmethyl)-2-methoxyaniline derivatives.
   Mikata, Y.; Tosaka, N.; Yasuda, S.; Sakurai, Y.; Shoji, S.; Konno, H.; Matsuo, T. Inorg. Chem. in press.
   
   
2. Cd²⁺-selective fluorescence enhancement of N, N'-bis(2-quinolylmethyl)-N, N'-dimethyl-1,2-phenylenediamine derivatives.
   Mikata, Y.; Kawakami, K.; Nagaoka, M.; Shoji, S.; Konno, H.; Matsuo, T. Inorg. Chim. Acta. 2024, 565(24), 121968(1)-121968(11).
   
   

1. Conformation state-specific monobodies regulate the functions of flexible proteins through conformation trapping
   Nakamura, I.; Amesaka, H.; Hara, M.; Yonezawa, K.; Okamoto, K.; Kamikubo, H.; Tanaka, S.-I.; Matsuo, T. Protein Sci. 2023, 32 (12), e4813(1)-e4813(16).
   
   
2. Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping.
   Sakai, T.; Mashima, T.; Kobayashi, N.; Ogata, H.; Duan, L.; Fujiki, R.; Hengphasatporn, K.; Uda, T.; Shigeta, Y.; Hifumi, E.; Hirota, S. Nat. Commun. 2023, 14, 7807(1)-7807(12).
   
   
3. Reactivity regulation for olefin metathesis-catalyzing ruthenium complexes with sulfur atoms at the terminal of 2-alkoxybenzylidene ligands.
   Kinugawa, T.; Matsuo, T. Dalton Trans. 2023, 52 (27), 9499-9508.
   
   
4. Effect of methoxy substituents on fluorescent Zn2+/Cd2+ selectivity of bisquinoline derivatives with a N,N'-dimethylalkanediamine skeleton
   Mikata, Y.; Tanaka, M.; Yasuda, S.; Tsuruta, A.; Hagiwara, T.; Konno, H.; Matsuo, T. Daltron Trans. 2023, 52(22), 11375-11388. 　　　　　　　
   
   

1. AlphaFold時代の生成モデルが身近にするタンパク質設計（デザイン）
   小林　直也、佐久間　航也, 実験医学.10月号
   
   　　　　　　　
2. Protein Cages and Nanostructures Constructed from Protein Nanobuilding Blocks
   Kobayashi, M.; Arai, R.
   "Protein Cages Design, Structure, and Applications; pp. 79-94, Hamana, New York, NY.

1. Structural and Spectroscopic Characterization of CO Inhibition of [NiFe]-Hydrogenase from Citrobacter sp. S-77
   Imanishi, T.; Nishikawa, K.; Taketa, M.; Higuchi, K.; Tai, H.; Hirota, S.; Hojo, H.; Kawakami, T.; Hataguchi, K.; Matsumoto, K.; Ogata, H.; Higuchi, Y. Acta Crystal. F 2022, 78(2), 66-74.
   
   
2. Heme-Bound Tyrosine Vibrations in Hemoglobin M: Resonance Raman, Crystallography and DFT Calculation
   Nagatomo, S.; Shoji, M.; Terada, T.; Nakatani, K.; Shigeta, Y.; Hirota, S.; Yanagisawa, S.; Kubo, M.; Kitagawa, T.; Nagai M.; Ohki, M; Park, S.-Y.; Shibayama N. Biophys. J. 2022, 121(14), 2767-2780.
   
   
3. Structural Region Essential for Amyloid Fibril Formation in Cytochrome c Elucidated by Optical Trapping
   Hirota, S.; Chiu, C.-L.; Chang, C.-J.; Lo, P.-H.; Chen, T.; Yang, H.; Yamanaka, M.; Mashima, T.; Xie, C.; Masuhara, H.; Sugiyama, T. Chem. Commun. 2022, 58(92), 12839-12842.
   
   
4. Cd2+-selective fluorescence response of TQEN (N,N,N',N'-tetrakis(2-quinolylmethyl)ethylenediamine) derivatives bearing ether oxygen-binding site
   Mikata, Y.; Kaneda, M.; Yonemura, S.; Akedo, M.; Konno, H.; Matsuo, T. Daltron Trans. 2022, 51, 17170-17179.
   
   

Reviews (International achievements only)

1. Second and Outer Coordination Sphere Effects in Nitrogenase, Hydrogenase, Formate Dehydrogenase, and CO Dehydrogenase
   Stripp, S. T.; Duffus, B.R.; Fourmond, V.; Léger, C.; Leimkühler, S.; Hirota, S.; Hu., Y.; Jasniewsk, A.; Ogata, H.; Ribbe, M. Chem. Rev. 2022, 122(14), 11900-11973.
   
   

1. Rational Design of Metal-Binding Sites in Domain-Swapped Myoglobin Dimers
   Nagao, S.; Idomoto, A.; Shibata, N.; Higuchi, Y.; Hirota, S. J. Inorg. Biochem. 2021, 217, 111374.
   
   
2. Construction of Ferritin Hydrogels Utilizing Subunit–Subunit Interactions
   Yamanaka, M.; Mashima, T.; Ogihara, M.; Okamoto, M.; Uchihashi, T.; Hirota, S. PLoS One 2021, 16(11), e0259052.
   
   
3. Experimental and Theoretical Study on Converting Myoglobin into a Stable Domain-Swapped Dimer by Utilizing a Tight Hydrogen Bond Network at the Hinge Region
   Xie, C.; Shimoyama, H.; Yamanaka, M.; Nagao, S.; Komori, H.; Shibata, N.; Higuchi, Y.; Shigeta, Y.; Hirota, S. RSC Advances 2021, 11(5), 37604-37611.
   
   

Reviews (International achievements only)

1. New Aspects of Cytochrome c: 3D Domain Swapping, Membrane Interaction, Peroxidase Activity, and Met80 Sulfoxide Oxidation
   Hirota, S.; Nagao, S. Bull. Chem. Soc. Jpn. (Award Account) 2021, 94(1), 170-182 (Featured on Inside Cover).
   
   
2. Proton Transfer Mechanisms in Bimetallic Hydrogenases
   Tai, H.; Hirota, S.; Stripp, S. Acc. Chem. Res. 2021, 54(1), 232-241.
   
   
3. Functionalization of Ruthenium Olefin-metathesis Catalysts for Interdisciplinary Studies in Chemistry and Biology
   Matsuo, T. Catalysts 2021, 11(3), 359(1)-359(25) (special issue on "Converging Chemistry and Biology: Chemoenzymatic Cascade Reactions and Biohybrid Catalysts").
   
   
4. Functionalization of Hoveyda-Grubbs-type Complexes for Application to Biomolecules
   Matsuo, T.J. Synth. Org. Chem. Jpn. (in Japanese) 2021, 79(4), 311-321.
   
   
5. Use of 3D Domain Swapping in Constructing Supramolecular Metalloproteins
   Hirota, S.; Mashima, T.; Kobayashi, N. Chem. Commun. (Future Article) 2021, 57(91), 12074-12086.
   
   

1. Regioselective Chemical Modification of Cysteine Residues on Protein Surfaces Focusing on Local Environment around the Conjugation Site
   Miyake, T.; Tamaki, R.; Asanuma, M.; Fukada, Y.; Hirota, S.; Matsuo, T. Bioconjugate Chem. 2020, 31(3), 794-802.
   
   
2. 3D Domain Swapping of Azurin from Alcaligenes xylosoxidans
   Cahyono, R. N.; Yamanaka, M.; Nagao, S.; Shibata, N.; Higuchi, Y.; Hirota, S. Metallomics 2020, 12(3), 337-345. (Featured on “Front Cover”)
   
   
3. Thermodynamic Control of Domain Swapping by Modulating Helical Propensity in the Hinge Region of Myoglobin
   Nagao, S.; Suda, A.; Kobayashi, H.; Shibata, N.; Higuchi, Y.; Hirota, S. Chem. Asian J. 2020, 15(11), 1743-1749. (Selected as “Very Important Paper”)
   
   
4. Second-Coordination Sphere Effects on the Reactivities of Hoveyda–Grubbs-Type Catalysts: A Ligand Exchange Study Using Phenolic Moiety-Functionalized Ligands
   Jatmika, C.; Goshima, K.; Wakabayashi, K.; Akiyama, N.; Hirota, S.; Matsuo, T. Dalton Trans. 2020, 49(33), 11618-11627.
   
   
5. Ligand Exchange Strategy for Delivery of Ruthenium Complex Unit to Biomolecules Based on Ruthenium-Olefin Interactions
   Jatmika, C.; Wakabayashi, K.; Tamaki, R.; Nakamura, I.; Akiyama, N.; Hirota, S.; Yamaguchi, H.; Matsuo, T. Chem. Lett. 2020, 49(12), 1490-1493.
   
   

Reviews (International achievements only)

1. Mechanism and Application of the Catalytic Reaction of [NiFe] Hydrogenase: Recent Developments
   Tai, H.; Hirota, S. ChemBioChem (Concept) 2020, 21(11), 1573-1581. (Selected as “Very Important Paper”)
   

1. Conferment of CO-controlled Dimer–Monomer Transition Property to Thermostable Cytochrome c' by Mutation in the Subunit–Subunit Interface
   Yamanaka, M.; Nakayama, R.; Fujii, S.; Wakai, S.; Sambongi, Y.; Hirota, S. Bull. Chem. Soc. Jpn. 2019, 92(3), 702-709.
   
   
2. Construction of a Quadrangular Tetramer and a Cage-Like Hexamer from Three-Helix Bundle-Linked Fusion Proteins
   Miyamoto, T.; Hayashi, Y.; Yoshida, K.; Watanabe, H.; Uchihashi, T.; Yonezawa, K.; Shimizu, N.; Kamikubo, H.; Hirota, S. ACS Synth. Biol. 2019, 8(5), 1112-1120.
   
   
3. Domain-Swapping Design by Polyproline Rod Insertion
   Shiga, S.; Yamanaka, M.; Fujiwara, W.; Hirota, S.; Goda, S.; Makabe, K. ChemBioChem 2019, 20(19), 2454-2457.
   
   
4. Protein Surface Charge Effect on 3D Domain Swapping in Cells for c-type Cytochromes
   Yang, H.; Yamanaka, M.; Nagao, S.; Yasuhara, K.; Shibata, N.; Higuchi, Y.; Hirota, S. Biochim. Biophys. Acta-Proteins Proteom. 2019, 1867(11),140265
   
   
5. Cysteine SH and Glutamate COOH Contributions to [NiFe] Hydrogenase Proton Transfer Revealed by Highly Sensitive FTIR Spectroscopy
   Tai, H.; Nishikawa, K.; Higuchi, Y.; Mao, Z.-w.; Hirota, S. Angew. Chem. Int. Ed. 2019, 58(38),13285-13290.
   
   
6. Determination of Proton Concentration at Cardiolipin-Containing Membrane Interfaces and Its Relation with the Peroxidase Activity of Cytochrome c
   Parui, P. P.; Sarakar, Y.; Majumder, R.; Das, S.; Yang, H.; Yasuhara, K.; Hirota, S. Chem. Sci. 2019, 10(39), 9140-9051.
   
   

Reviews (International achievements only)

1. Oligomerization of Cytochrome c, Myoglobin, and Related Heme Proteins by 3D Domain Swapping
   Hirota, S. J. Inorg. Biochem. 2019, 194, 170-179.
   
   
2. Recent Developments on Creation of Artificial Metalloenzymes
   Matsuo, T.; Miyake, T.; Hirota, S. Tetrahedron Lett. 2019, 60, 151226 (8 pages).
   
   

1. Theoretical Analysis of the Domain-Swapped Dimerization of Cytochrome c: An MD and 3D-RISM Approach
   Yoshida, N.; Higashi, M.; H. Motoki H.; Hirota, S. J. Chem. Phys. 2018, 148(2), 025102 (7 pages).
   
   
2. Global Structural Flexibility of Metalloproteins Regulates Reactivity of Transition Metal Ion in the Protein Core: An Experimental Study Using Thiol-subtilisin as a Model Protein
   Matsuo, T.; Kono, T.; Shobu, I.; Ishida, M.; Gonda, K.; Hirota, S. Eur. J. Chem. 2018, 24(11), 2767-2775.
   
   
3. Oxidative Modification of Methionine80 in Cytochrome c by Reaction with Peroxides
   Nugraheni, A. D.; Ren, C.; Matsumoto, Y.; Nagao, S.; Yamanaka, M.; Hirota, S. J. Inorg. Biochem. 2018, 182, 200-207.
   
   
4. Construction of a Triangle-Shaped Trimer and a Tetrahedron Using an α-Helix-Inserted Circular Permutant of Cytochrome c₅₅₅
   Oda, A.; Nagao, S.; Yamanaka, M.; Ueda, I.; Watanabe, H.; Uchihashi, T.; Shibata, N.; Higuchi, Y.; Hirota, S. Chem. Asian J. 2018, 13(8), 964-967. Featured on “Front Cover”.
   
   
5. Redox-dependent Conformational Changes of a Proximal [4Fe–4S] Cluster in Hyb-type [NiFe]-hydrogenase to Protect the Active Site from O₂
   Noor, N. D. M.; Matsuura, H.; Nishikawa, K.; Tai, H.; Hirota, S.; Kim, J.; Kang, J.; Tateno, M.; Yoon, K.-S.; Ogo, S.; Kubota, S.; Shomura, Y.; Higuchi, Y. Chem. Commun. 2018, 54(87), 12385-12388.
   
   
6. Synergistic Effect of Distal Polar Interactions in Myoglobin and Their Structural Consequences
   Watanabe, M.; Kanai, Y.; Nakamura, S.; Nishimura, R.; Shibata, T.; Momotake, A.; Yanagisawa, S.; Ogura, T.; Matsuo, T.; Hirota, S.; Neya, S.; Suzuki, A.; Yamamoto Y. Inorg. Chem. 2018, 57(22), 14269-14279.
   
   

Reviews (International achievements only)

1. Design of Artificial Metalloproteins/Metalloenzymes by Tuning Noncovalent Interactions
   Hirota, S.; Lin, Y.-W. J. Biol. Inorg. Chem. 2018, 23(1), 7-25.
   
   
2. Comprehensive Reaction Mechanisms at and nearby the Ni‒Fe Active Sites of [NiFe] Hydrogenases
   Tai, H.; Higuchi, Y.; Hirota, S. Dalton Trans. (Perspective) 2018, 47(13), 4408-4423.
   

1. Formation and Carbon Monoxide-Dependent Dissociation of Allochromatium vinosum Cytochrome c’ Oligomers Using Domain-Swapped Dimers
   Yamanaka, M.; Hoshizumi, M.; Nagao, S.; Nakayama, R.; Shibata, N.; Higuchi, Y.; Hirota, S. Protein Sci. 2017, 26(3), 464-474.
   
   
2. Improved Stopped-Flow Time-Resolved Resonance Raman Spectroscopy Device for Studying Enzymatic Reactions
   Yanagisawa, S. Deshpande, M. S.; Hirota, S.; Nakagawa, T.; Ogura, T. J. Raman Spectrosc. 2017, 48(5), 680-685.
   
   
3. Effect of Methionine80 Heme Coordination on Domain Swapping of Cytochrome c
   Hirota, S.; Yamashiro, N.; Wang, Z.; Nagao, S. J. Biol. Inorg. Chem. 2017, 22(5), 705-712.
   
   
4. A Single Spherical Assembly of Protein Amyloid Fibrils Formed by Laser Trapping
   Yuyama, K.; Ueda, M.; Nagao, S.; Hirota, S.; Sugiyama, T.; Masuhara, H. Angew. Chem. Int. Ed. 2017, 56(24), 6739-6743. Selected as "Hot Paper".
   
   
5. Structural Basis of the Redox Switches in the NAD+-Reducing Soluble [NiFe]-Hydrogenase
   Shomura, Y.; Taketa, M.; Nakashima, H.; Tai, H.; Nakagawa, H.; Ikeda, Y.; Ishii, M.; Igarashi, Y.; Nishihara, H.; Yoon, K.-S.; Ogo, S.; Hirota, S.; Higuchi, Y. Science 2017, 357(6354), 928-932.
   
   
6. Rational Design of Domain-Swapping-Based c-Type Cytochrome Heterodimers by Using Chimeric Proteins
   Zhang, M.; Nakanishi, T.; Yamanaka, M.; Nagao, S.; Yanagisawa, S.; Shomura, Y.; Shibata, N.; Ogura, T.; Higuchi, Y.; Hirota, S. ChemBioChem 2017, 18(17), 1712-1715.
   
   
7. Equilibrium between Inactive Ready Ni-SIr and Active Ni-SIa States of [NiFe] Hydrogenase Studied by Utilizing Ni-SIr-to-Ni-SIa Photoactivation
   Tai, H.; Xu, L.; Nishikawa, K.; Higuchi, Y.; Hirota, S. Chem. Commun 2017, 53(75), 10444-10447.
   
   
8. Activation Mechanism of Streptomyces Tyrosinase Assisted by the Caddie Protein
   Matoba, Y.; Kihara, S.; Muraki, Y.; Bando, N.; Yoshitsu, H.; Kuroda, T.; Sakaguchi, M.; Kayama, K.; Tai, H.; Hirota, S.; Ogura, T.; Sugiyama, M. Biochemistry 2017, 56(41), 5593-5603.
   
   
9. Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity
   Iwase, T.; Matsuo, T.; Nishioka, S.; Tajima, A.; Mizunoe, Y. Front Microbiol 2017, 8, 656.
   

1. Domain swapping oligomerization of thermostable c-type cytochrome in E. coli cells
   Hayashi, Y.; Yamanaka, M.; Nagao, S.; Komori, H.; Higuchi, Y.; Hirota, S. Sci. Rep. 2016, 6, 19334 (8 pages).
   
   
2. Effect of Heme Electronic Structure and Distal Polar Interaction on Functional and Vibrational Properties of Myoglobin
   Kanai, Y.; Nishimura, R.; Nishiyama, K.; Shibata, T. Yanagisawa, S.; Ogura, T.; Matsuo, T.; Hirota, S.; Neya, S.; Suzuki, A.; Yamamoto, Y. Inorg. Chem. 2016, 55, 1613-1622.
   
   
3. A Simple Interfacial pH Detection Method for Cationic Amphiphilic Self-assemblies Utilizing a Schiff-base Molecule
   Sarkar, Y. ; Das, S.; Ray, A.; Jewrajka, S. K.; Hirota, S.; Parui, P. P. Analyst 2016, 141, 2030-2039.
   
   
4. Photoactivation of the Ni-SIr State to the Ni-SIa State in [NiFe] Hydrogenase: FT-IR Study on the Light Reactivity of the Ready Ni-SIr State and As-isolated Enzyme Revisited
   Tai, H.; Xu, L.; Nishikawa, K.; Inoue, S.; Higuchi, Y.; Hirota, S. Phys. Chem. Chem. Phys. 2016, 18, 22025 - 22030.
   
   
5. Characterization of Cytochrome c Membrane-Binding Site Using Cardiolipin-Containing Bicelles with NMR
   Kobayashi, H.; Nagao, S.; Hirota, S. Angew. Chem. Int. Ed. 2016, 55, 14019-14022.
   
   

1. Rational Design of Heterodimeric Protein Using Domain Swapping for Myoglobin
   Lin, Y.-W.; Nagao, S.; Zhang, M.; Shomura, Y.; Higuchi, Y.; Hirota, S. Angew. Chem. Int. Ed. 2015, 54, 511-515.
   
   
2. Change in Structure and Ligand Binding Properties of Hyperstable Cytochrome c₅₅₅ from Aquifex aeolicus by Domain Swapping
   Yamanaka, M.; Nagao, S.; Komori, H.; Higuchi, Y.; Hirota, S. Protein Sci. 2015, 24, 366-375.
   
   
3. Carbon Monoxide Binding Properties of Domain-Swapped Dimeric Myoglobin Nagao, S.; Ishikawa, H.; Yamada, T.; Mizutani, Y.; Hirota, S. J. Biol. Inorg. Chem. 2015, 20, 253-530.
   
   
4. Dimer Domain Swapping versus Monomer Folding in Apo-myoglobin Studied by Molecular Simulations
   Ono, K.; Ito, M.; Hirota, S.; Takada, S. Phys. Chem. Chem. Phys. 2015, 17, 5006-5013.
   
   
5. Excimer Emission Properties on Pyrene-labeled Protein Surface: Correlation between Emission Spectra, Ring Stacking Modes and Flexibilities of Pyrene Probes
   Fujii, A.; Sekiguchi, Y.; Matsumura, H.; Inoue, T.; Chung, WS.; Hirota, S.; Matsuo, T. Bioconjugate Chem. 2015, 26, 537-48.
   
   
6. Domain-Swapped Dimer of Pseudomonas aeruginosa Cytochrome c₅₅₁: Structural Insights into Domain Swapping of Cytochrome c Family Proteins
   Nagao, S.; Ueda, M.; Osuka, H.; Komori, H.; Kamikubo, H.; Kataoka, M.; Higuchi, Y.; Hirota, S. PLoS One 2015, 10, e0123653.
   
   
7. Effect of a Procaspase-Activating Compound on the Catalytic Activity of Mature Caspase-3
   Matsuo, T.; Yamada, K.; Ishida, M.; Miura, Y.; Yamanaka, M.; Hirota, S. Bull. Chem. Soc. Jap. 88, 2015, 1221-1229. BCSJ award
   
   
8. Domain-swapped Cytochrome cb₅₆₂ Dimer and Its Nanocage Encapsulating a Zn–SO₄ Cluster in the Internal Cavity
   Miyamoto, T.; Kuribayashi, M.; Nagao, S.; Shomura, Y.; Higuchi, Y.; Hirota, S. Chem. Sci. 2015, 6, 7336-7342.
   
   
9. Oligomerization Enhancement and Two Domain Swapping Mode Detection for Thermostable Cytochrome c₅₅₂ via the Elongation of the Major Hinge Loop
   Ren, C.; Nagao, S.; Yamanaka, M.; Komori, H.; Shomura, Y.; Higuchi, Y., Hirota, S. Mol. Biosyst. 2015, 11, 3218-3221.
   
   
10. FT-IR Characterization of the Light-Induced Ni-L2 and Ni-L3 States of [NiFe] Hydrogenase from Desulfovibrio vulgaris Miyazaki F
    Tai, H.; Nishikawa, K.; Inoue, S.; Higuchi, Y.; Hirota, S. J. Phys. Chem. B 2015, 119, 13668-13674.
    
    
    

1. Self-Assembled Dimerization of Bis(crown ether)-2,2’-bibenzimidazoles
   Satake, A.; Tanaka, K.; Asakura, H.; Okano, M.; Hashimoto, T,; Matsuura, Y.; Inaba, Y.; Oda, T.; Hirota, S.; Koshino, H. Bull. Chem. Soc. Jpn. 2014, 87, 88-97.
   
   
2. Electronic Control of Discrimination between O₂ and CO in Myoglobin the Lacking Distal Histidine Residue
   Nishimura, R.; Shibata, T.; Ishigami, I.; Ogura, T.; Tai, H.; Nagao, S.; Matsuo, T.; Hirota, S.; Shoji, O.; Watanabe, Y.; Imai, K.; Neya, S.; Suzuki, A.; Yamamoto, Y. Inorg. Chem. 2014, 53, 1091–1099.
   
   
3. H₂O₂-dependent Substrate Oxidation by an Engineered Diiron Site in a Bacterial Hemerythrin
   Okamoto, Y.; Onoda, A.; Sugimoto, H.; Takano, Y.; Hirota, S.; Kurtz, Jr., D. M.; Shiro, Y.; Hayashi T., Chem. Commun. 2014, 50, 3421-3423.
   
   
4. Morphological Change of Cell Membrane by Interaction with Domain-Swapped Cytochrome c Oligomers
   Junedi, S.; Yasuhara, K.; Nagao, S.; Kikuchi, J., Hirota, S. ChemBioChem 2014, 15, 517-521.
   
   
5. Formation of Domain-Swapped Oligomer of Cytochrome c from Its Molten Globule State Oligomer
   Deshpande, M. S.; Parui, P. P.; Kamikubo, H.; Yamanaka, M.; Nagao, S.; Komori, H.; Kataoka, M.; Higuchi, Y.; Hirota, S. Biochemistry 2014, 53, 4696-4703.
   
   
6. Electronic Control of Ligand-Binding Preference of a Myoglobin Mutant
   Nishimura, R.; Matsumoto, D.; Shibata, T.; Yanagisawa, S.; Ogura, T.; Tai, H.; Matsuo, T.; Hirota, S.; Neya, S.; Suzuki, A.; Yamamoto, Y. Inorg. Chem. 2014, 53, 9156-9165.
   
   
7. Self-Oxidation of Cytochrome c at Methionine80 with Molecular Oxygen Induced by Cleavage of the Met−Heme Iron Bond
   Wang, Z.; Ando, Y.; Nugraheni, A. D.; Ren, C.; Nagao, S.; Hirota, S. Mol. BioSyst. 2014, 10, 3130-3137.
   
   
8. DNA Cleavage by Oxymyoglobin and Cysteine-Introduced Metmyoglobin
   Deshpande, M. S.; Junedi, S.; Prakash, H.; Nagao, S.; Yamanaka, M.; Hirota, S.Chem. Commun. 2014, 50, 15034-15036.
   
   
9. Control of the Transition between Ni-C and Ni-SIa States by the Redox State of the Proximal Fe-S Cluster in the Catalytic Cycle of [NiFe] Hydrogenase
   Tai, H.; Nishikawa, K.; Suzuki, M.; Higuchi, Y.; Hirota, S., Angew. Chem. Int. Ed. 2014, 53, 13817-13820.
   
   
10. Structural characterization of imidazole adducts of heme-DNA complexes
    Suzuki, Y.; Tai, H.; Saito, K.; Shibata, T.; Kinoshita, M.; Suzuki, A.; Yamamoto, Y., J. Porphyrins Phthalocyanines 2014, 18, 741-751.
    
    
11. Effect of the electron density of the heme Fe atom on the Fe-histidine coordination bond in deoxy myoglobin
    Nishimura, R.; Shibata, T.; Tai, H.; Ishigami, I.; Yanagisawa, S.; Ogura, T.; Neya, S.; Suzuki, A.; Yamamoto, Y., Bull. Chem. Soc. Jpn. 2014, 87, 905-911.
    
    

Reviews (International achievements only)

1. Artificial Enzymes with Protein Scaffolds: Structural Design and Modification
   Matsuo, T.; Hirota, S. Bioorg. Med. Chem. 2014, 22, 5638-5656.
   

1. Photosensitivity of the Ni-A state of [NiFe] hydrogenase from Desulfovibrio vulgaris Miyazaki F with visible light
   Osuka, H.; Shomura, Y.; Komori, H.; Shibata, N.; Nagao, S.; Higuchi, Y.; Hirota, S. Biochem. Biophys. Res. Commun. 2013, 430, 284-288.
   
   
2. Interaction of dimeric horse cytochrome c with cyanide ion
   Nugraheni, A.D.; Nagao, S.; Yanagisawa, S.; Ogura, T.; Hirota, S. J. Biol. Inorg. Chem. 2013, 18, 383-390.
   
   
3. Relationship between the electron density of the heme Fe atom and the vibrational frequencies of the Fe-bound carbon monoxide in myoglobin
   Nishimura, R.; Shibata, T.; Tai, H.; Ishigami, I.; Ogura, T.; Nagao, S.; Matsuo, T.; Hirota, S.; Imai, K.; Neya, S.; Suzuki, A.; Yamamoto, Y.; Inorg. Chem. 2013, 52, 3349-3355.
   
   
4. Reversible switching of fluorophore property based on intrinsic conformational transition of adenylate kinase during its catalytic cycle
   Fujii, A.; Hirota, S.; Matsuo, T. Bioconjug. Chem. 2013, 24, 1218-1225.
   
   
5. Effect of Added Salt on Ring-closing Metathesis Catalyzed by a Water-soluble Hoveyda-Grubbs Type Complex to Form N-Containing Heterocycles in Aqueous Media
   Matsuo, T.; Yoshida, T.; Fujii, A.; Kawahara, K.; Hirota, S. Organometallics 2013, 32, 5313-5319.
   
   　　　　　　　
6. Crystal Structure, Exogenous Ligand Binding and Redox Properties of an Engineered Diiron Active Site in a Bacterial Hemerythrin
   Okamoto, Y.; Onoda, A.; Sugimoto, H.; Takano, Y.; Hirota, S.; Kurtz, Jr., D. M.; Shiro, Y,; Hayashi, T. Inorg. Chem. 2013, 52, 13014-13020.
   　　　　　　　
   
7. Formation of Oligomeric Cytochrome c during Folding by Intermolecular Hydrophobic Interaction between N- and C-Terminal α-Helices
   Parui, P. P.; Deshpande, M. S.; Nagao, S.; Kamikubo, H.; Komori, H.; Higuchi, Y.; Kataoka, M.; Hirota, S. Biochemistry 2013, 52, 8732-8744.
   
   
8. NMR Spectroscopic Study of the Complexation Behaviors of Deuterated Cyclodextrins and [60]Fullerene
   Ikeda, A.; Hida, T.; Kikuchi, J.; Nobusawa, K.; Matsuo, T.; Org. Lett. 2013, 15, 6194-6197.
   
   

1. Creation of an Artificial Metalloprotein with a Hoveyda-Grubbs Catalyst Moiety through the Intrinsic Inhibition Mechanism of α-Chymotrypsin
   Matsuo, T.; Imai, C.; Yoshida, T.; Saito, T.; Hayashi, T. Hirota, S. Chem. Commun. 2012, 48, 1662-1664.
   
   
2. Structural and Oxygen Binding Properties of Dimeric Horse Myoglobin
   Nagao, S.; Osuka, H.; Yamada, T.; Uni, T.; Shomura, Y.; Higuchi, Y.; Hirota, S. Dalton Trans. 2012, 41, 11378-11385.
   
   
3. Domain Swapping of the Heme and N-terminal α-helix in Hydrogenobacter thermophilus Cytochrome c₅₅₂ Dimer
   Hayashi, Y.; Nagao, S.; Osuka, H.; Komori, H.; Higuchi, Y.; Hirota, S. Biochemistry 2012, 51, 8608-8616.
   
   
4. Relationship between Oxygen Affinity and Autoxidation of Myoglobin
   Shibata, T.; Matsumoto, D.; Nishimura, R.; Tai, H.; Matsuoka, A.; Nagao, S.; Matsuo, T.; Hirota, S.; Imai, K.; Neya, S.; Suzuki, A.; Yamamoto, Y. Inorg. Chem. 2012, 51, 11955-11960.
   
   
5. Efficient Oxidative Cycloreversion Reaction of Photochromic Dithiazolythiazole
   Nakashima, T.; Kajiki, Y.; Fukumoto, S.; Taguchi, M.; Nagao, S.; Hirota, S.; Kawai, T. J. Am. Chem. Soc. 2012, 134, 19877-19883.
   
   
6. Maintenance of the Secondary Structure of Horse Cytochrome c during the Conversion Process of Monomers to Oligomers by Addition of Ethanol
   Hirota, S.; Ueda, M.; Hayashi, Y.; Nagao, S.; Kamikubo, H.; Kataoka, M. J. Biochem. 2012, 152, 521-529.
   
   
7. Field-dependent ¹⁹F NMR Study of Sperm Whale Myoglobin Reconstituted with Ring-fluorinated Heme
   Yamamoto, Y.; Nagao, S.; Hirai, Y.; Tai, H.; Suzuki, A. Polymer J. 2012, 44, 907-912.
   
   
8. Reaction Pathway and Free Energy Profile for Conversion of pi-Conjugation Modes in Porphyrin Isomer
   Matsuo, T.; Tohi, Y.; Hayashi, T. J. Org. Chem. 2012, 77, 8946-8955.
   　　　　
   
9. Reaction of Cobalt Porphycene with Hydride Reagents: Spectroscopic Detection of Co–H Porphycene Species and Formation of Co–SnR₃ Porphycene Species
   Matsuo, T.; Komatsuzaki, K.; Tsuji, T.; Hayashi, T. J. Pophyrins. Phthalocyanines. 2012, 16, 616-625.
   
   
10. Synthesis of Rhenium(I) Tricarbonyl Complexes with Carbohydrate-Pendant Tridentate Ligands and their Cellular Uptake
    Mikata, Y.; Takahashi, K.; Noguchi, Y.; Naemura, M.; Ugai, A.; Itami, S.; Yasuda, K.; Tamotsu, S.; Matsuo, T.; Storr, T. Eur.J. Inorg. Chem. 2012, 217-225.
    
    

1. Supramolecular Organization of Light-Harvesting Porphyrin Macrorings
   Satake, A.; Azuma, S.; Kuramochi, Y.; Hirota, S.; Kobuke, Y. Chem. Eur. J. 2011, 17, 855-865.
   
   
2. Enhancement of Laccase Activity through the Construction and Breakdown of a Hydrogen Bond at the Type I Copper Center in Escherichia coli CueO and the Deletion Mutant Δα5-7 CueO
   Kataoka, K.; Hirota, S.; Maeda, Y.; Kogi, H.; Shinohara, N.; Sekimoto, M.; Sakurai, T. Biochemistry 2011, 50, 558-565.
   
   
3. Post-translational His-Cys Cross-Linkage Formation in Tyrosinase Induced by Copper(II)-Peroxo Species
   Fujieda, N.; Ikeda, T.; Murata, M.; Yanagisawa, S.; Aono, S.; Okubo, K.; Nagao, S.; Ogura, T.; Hirota, S.; Fukuzumi, S.; Nakamura, Y.; Hata, Y.; Itoh, S. J. Am. Chem. Soc. 2011, 133, 1180-1183.
   
   
4. Efficient Reduction of Cys110 Thiyl Radical by Glutathione in Human Myoglobin
   Nagao, S.; Asami, O.; Yasui, H.; Hirota, S. Biochim. Biophys. Acta – Proteins and Proteomics 2011, 1814, 480-486.
   
   
5. Peroxidase Activity Enhancement of Horse Cytochrome c by Dimerization
   Wang, Z.; Matsuo, T.; Nagao, S.; Hirota, S. Org. Biomol. Chem. 2011, 9, 4766-4769.
   
   
6. DNA Cleavage by the Photocontrolled Cooperation of ZnII Centers in an Azobenzene-Linked Dizinc Complex
   Panja, A.; Matsuo, T.; Nagao, S.; Hirota, S. Inorg. Chem. 2011, 50, 11437-11445.
   
   
7. Thermal Isomerization of N-Bridged Cobalt Corrole Complexes through Transiently Formed Axial Carbenoid
   Chattopadhyay, P.; Matsuo, T; Tsuji, T.; Ohbayashi, J.; Hayashi, T. Organometallics 2011, 30, 1869-1873.
   
   
8. Precise Design of Artificial Cofactors for Enhancing Peroxidase Activity of Myoglobin: Myoglobin Mutant H64D Reconstituted with a Single-winged Cofactor is Equivalent to Native Horseradish Peroxidase in Oxidation Activity
   Matsuo, T; Fukumoto, K.; Watanabe, T.; Hayashi, T. Chem. Asian. J. 2011, 6, 2491-2499. [INSIDE COVER FIGURE]
   　　　　
   
9. Investigation of Aromaticity and Photophysical Properties in [18]/[20]pi-Porphycene Derivatives
   Kim, K. S.; Sung, Y. M.; Matsuo, T.; Hayashi, T.; Kim, D. Chem. Eur. J. 2011, 17, 7882-7889.
   　　　　
   
   

1. Supramolecular Protein–Protein Complexation via Specific Interaction Between Glycosylated Myoglobin and Sugar-binding Protein
   Nagai, H.; Onoda, A.; Matsuo, T.; Hayashi, T. Supramol. Chem. 2010, 22, 57-64.
   
   
2. Reduction of Bis(dithiolene)oxo(disulfido)tungsten(VI) Complex with Dihydrogen Related to the Chemical Function of the Fourth Tungsten–Containing Enzyme (WOR4) from Pyrococcus furiosus
   Sugimoto, H.; Tano, H.; Toyota, K.; Tajima, R.; Miyake, H.; Takahashi, I.; Hirota, S.; Itoh, S. J. Am. Chem. Soc. 2010, 132, 8-9.
   
   
3. Effect of Heme Modification on Oxygen Affinity of Myoglobin and Equilibrium of the Acid-Alkaline Transition in Metmyoglobin
   Shibata, T.; Nagao, S.; Fukaya, M.; Tai, H.; Nagatomo, S.; Morihashi, K.; Matsuo, T.; Hirota, S.; Suzuki, A.; Imai, K.; Yamamoto, Y. J. Am. Chem. Soc. 2010, 132, 6091-6098.
   
   
4. Coherent Dynamics and Ultrafast Excited State Relaxation of Blue Copper Protein; Plastocyanin
   Nagasawa, Y.; Fujita, K.; Katayama, T.; Ishibashi, Y.; Miyasaka, H.; Takabe, T.; Nagao, S; Hirota, S. Phys. Chem. Chem. Phys. 2010, 12, 6067-6075.
   
   
5. Structural Basis of the Lactate-Dependent Allosteric Regulation of Oxygen Binding in Arthropod Hemocyanin
   Hirota, S.; Tanaka, N.; Micetic, I.; Di Muro, P.; Nagao, S.; Kitagishi, H.; Kano, K.; Magliozzo, R. S.; Peisach, J.; Beltramini, M.; Bubacco, L. J. Biol. Chem. 2010, 285, 19338-19345.
   
   
6. Characterization of the Acid–alkaline Transition in the Individual Subunits of Human Adult and Foetal Methaemoglobins
   Shibata, T.; Nagao, S.; Tai, H.; Nagatomo, S.; Hamada, H.; Yoshikawa, H.; Suzuki, A.; Yamamoto, Y. J. Biochem. 2010, 148, 217-229.
   
   
7. Cytochrome c Polymerization by Successive Domain Swapping at the C-Terminal Helix
   Hirota, S.; Hattori, Y.; Nagao, S. Taketa, M.; Komori, H.; Kamikubo, H.; Wang, Z.; Takahashi, I.; Negi, S.; Sugiura, Y.; Kataoka, M.; Higuchi, Y. Proc. Natl. Acad. Sci. USA 2010, 107, 12854-12859.
   
   
8. Crystallization and Preliminary X-ray Analysis of Dimeric and Trimeric Cytochromes c from horse Heart
   Taketa, M.; Komori, H.; Hattori, Y.; Nagao, S.; Hirota, S.; Higuchi, Y. Acta. Crystallogr. Sect. F 2010, 66, 1477-1479.
   
   
9. New Class of Rhodamine Luminophore: Design, Syntheses and Aggregation-Induced Emission Enhancement
   Kamino, S.; Horio, Y.; Komeda, S.; Minoura, K.; Ichikawa, H.; Horigome, J.; Tatsumi, A.; Kaji, S.; Yamaguchi, T.; Usami, Y.; Hirota, S.; Enomoto, S.; Fujita, Y. Chem. Commun. 2010, 46, 9013-9015.
   
   
10. Oxoferryl Porphyrin/Hydrogen Peroxide System Whose Behavior is Equivalent to Hydroperoxoferric Porphyrin
    Kitagishi, H.; Tamaki, M.; Ueda, T.; Hirota, S.; Ohta, T.; Naruta, Y.; Kano, K. J. Am. Chem. Soc. 2010, 132, 16730–16732.
    
    

1. A Role of the Heme-7-Propionate Side Chain in Cytochrome P450cam as a Gate for Regulating the Access of Water Molecules to the Substrate-Binding Site
   Hayashi, T.; Harada, K.; Sakurai, K.; Shimada, H.; Hirota, S. J. Am. Chem. Soc. 2009, 131, 1398-1400.
   
   
2. Four-Electron Reduction of Dioxygen by a Multicopper Oxidase, CueO, and Roles of Asp112 and Glu506 Located Adjacent to the Trinuclear Copper Center
   Kataoka, K.; Sugiyama, R.; Hirota, S.; Inoue, M.; Urata, K; Minagawa, Y.; Seo, D.; Sakurai, T. J. Biol. Chem., 2009 284, 14405-14413.
   
   
3. Modulation of Protein-Ligand Interactions by Photocleavage of a Cyclic Peptide using Phosphatidylinositol 3-Kinase SH3 Domain as Model System
   Takahashi, I.; Kuroiwa, S.; Lindfors, H.; Ndamba, L. A.; Hiruma, Y.; Yajima, T.; Okishio, N.; Ubbink, M.; Hirota, S. J. Petp. Sci. 2009, 15, 411-416.
   
   
4. Electron Transfer from Cytochrome c to Cupredoxin
   Takayama, S. J.; Irie, K.; Tai, H.; Kawahara, T.; Hirota, S.; Takabe, T.; Alcaraz, J. A.; Donaire, A.; Yamamoto, Y. J. Biol. Inorg. Chem. 2009, 14, 821-828.
   
   
5. Regulating Copper-Binding Affinity with Photoisomerizable Azobenzene Ligand by Construction of a Self-Assembled Monolayer
   Takahashi, I; Honda, Y.; Hirota, S. Angew. Chem. Int. Ed. 2009, 48, 6065-6068.
   
   
6. Coordination-induced sliding motion of a complementary porphyrin-phthalocyanine dimer: fluorescence-based molecular switch
   Satake, A.; Sugimura, T.; Kobuke, Y. J. Porphyrins Phthalocyanines 2009, 13, 326-335.
   
   
7. Energy transfer followed by electron transfer in a porphyrin macrocycle and central acceptor ligand: A model for a photosynthetic composite of the light-harvesting complex and reaction center
   Kuramochi, Y.; Sandanayaka, Atula S. D.; Satake, A.; Araki, Y.; Ogawa, K.; Ito, O.; Kobuke, Y. Chem. Eur. J. 2009, 15, 2317-2327.
   
   
8. Single Supramolecular Porphyrin Wires Bridging Gold Nanoparticles
   Satake, A.; Fujita, M.; Kurimoto, Y.; Kobuke, Y. J. Inorg. Chem. 2009, 1231-1233.
   
   
9. Meso-Unsubstituted Iron Corrole in Hemoproteins: Remarkable Differences in Effects on Peroxidase Activities　between Myoglobin and Horseradish Peroxidase
   Matsuo, T.; Hayashi, A.; Abe, M.; Matsuda, T.; Hisaeda Y.; Hayashi, T. J. Am. Chem. Soc. 2009, 131, 15124-15125.
   
   

Reviews (International achievements only)

1. Electron Transfer and Oxidation Activities in Reconstituted Hemoproteins　with Chemically Modified Cofactor
   Matsuo, T.; Hayashi, T. J. Porphyrins Phthalocyanines 2009, 13, 1082-1089.
   
   

1. Evaluation of the Functional Role of the Heme-6-Propionate Side Chain in Cytochrome P450cam
   Harada, K.; Sakurai, K.; Ikemura, K.; Ogura, T.; Hirota, S.; Shimada, H.; Hayashi, T. J. Am. Chem. Soc. 2008, 130, 432-433.
   
   
2. H-atom Abstraction Reaction for Organic Substrates via Mononuclear Copper(II)-Superoxo Species as a Model for DbM and PHM
   Fujii, T.; Yamaguchi, S.; Hirota, S.; Masuda, H. Dalton Trans 2008, 164-170.
   
   
3. Development of Novel Water-Soluble Photocleavable Protective Group and Its Application for Design of Photoresponsive Paclitaxel Prodrugs
   Noguchi, M.; Skwarczynski, M.; Prakash, H.; Hirota, S.; Kimura, T.; Hayashi, Y.; Kiso, Y. Bioorg. Med. Chem. 2008, 16, 5389-5397.
   
   
4. Thermodynamics of Apoplastocyanin Folding: Comparison between Experimental and Theoretical Results
   Yoshidome, T.; Kinoshita, M.; Hirota, S.; Baden, N.; Terazima, M. J. Chem. Phys. 2008, 128, 225104.
   
   
5. Photocontrol of Spatial Orientation and DNA Cleavage Activity of Copper(II)-Bound Dipeptides Linked by an Azobenzene Derivative
   Prakash, H.; Shodai, A.; Yasui, H.; Sakurai, H.; Hirota, S. Inorg. Chem. 2008, 47, 5045-5047.
   
   
6. A Supramolecular Receptor of Diatomic Molecules (O2, CO, NO) in Aqueous Solution
   Kano, K.; Itoh, Y.; Kitagishi, H.; Hayashi, T.; Hirota, S. J. Am. Chem. Soc. 2008, 130, 8006-8015.
   
   
7. Stable Supramolecular Complex of Porphyrin Macroring with Pyridyl and Fullerenyl Ligands
   Zafer, U.; Satake, A.; Kobuke, Y.; Hirota, S. Tetrahedron Lett. 2008, 49, 5484-5487.
   
   
8. Syntheses, Characterization and Reactivities of μ-η2:η2-Disulfidodicopper(II) Complexes with N-Alkylated cis,cis-1,3,5-Triamionocyclohexane Derivatives
   Kajita, Y.; Matsumoto, J.; Takahashi, I.; Hirota, S.; Funahashi, Y.; Ozawa, T.; Masuda, H., Eur. J. Inorg. Chem. 2008, 3977-3986.
   
   
9. A New Class of Sulfido/oxo(dithiolene)–molybdenum(IV) Complexes Derived from Sulfido/Oxo–Bis(tetrasulfido)molydebnum(IV) Anions
   Sugimoto, H.; Suyama, K.; Sugimoto, K.; Miyake, H.; Takahashi, I.; Hirota, S.; Itoh, S. Inorg. Chem. 2008, 47, 10150-10157.
   
   
10. Molecular Basis of the Bohr Effect in Arthropod Hemocyanin
    Hirota, S.; Kawahara, T.; Beltramini, M.; Di Muro, P.; Magliozzo, R. S.; Peisach, J.; Powers, L. S.; Tanaka, N.; Nagao, S.; Bubacco, L. J. Biol. Chem. 2008, 283, 31941-31948.
    
    
11. Construction of Giant Porphyrin Macrorings Self-Assembled from Thiophenylene-Linked Bisporphyrins for Light-Harvesting Antenna
    Fujisawa, K.; Satake, A.; Hirota, S.; Kobuke, Y. Chem. Eur. J. 2008, 14, 10735-10744.
    
    
12. Formation of a Bridged Butterfly-Type μ-η2:η2-Peroxo Dicopper Core Structure with a Carboxylate Group
    Funahashi, Y.; Nishikawa, T.; Wasada-Tsutsui, Y.; Kajita, Y.; Yamaguchi, S.; Arii, H.; Ozawa, T.; Jitsukawa, K.; Tosha, T.; Hirota, S.; Kitagawa, T.; Masuda, H. J. Am. Chem. Soc. 2008, 130, 16444-16445.
    
    
13. Controlled Production of Amyloid β Peptide from a Photo-Triggered, Water-Soluble Precursor "Click Peptide"
    Taniguchi, A.; Skwarczynski, M.; Sohma, Y.; Okada, T.; Ikeda, K.; Prakash, H.; Mukai, H.; Hayashi, Y.; Kimura, T.; Hirota, S.; Matsuzaki, K.; Kiso, Y. ChemBioChem 2008, 9, 3055-3065.
    
    
14. Oxidation of Adamantane Catalysed by Imidazolylporphyrinatoiron(III) Complexes and Structural Studies of 5-Coordinating Iron(III) Porphyrin,
    Miyazaki, Y.; Satake, A.; Kobuke, Y. J. Mol. Cat. A: Chemical 2008, 283, 129-139.
    
    
15. Light-Harvesting Supramolecular Porphyrin Macroring Accommodating a Fullerene–Tripodal Ligand,
    Kuramochi, Y.; Satake, A.; Itou, M.; Ogawa, K.; Araki, Y.; Ito, O.; Kobuke, Y. Chem. Eur. J. 2008, 14, 2827-2841.
    
    
16. Transmembrane Nanopores from Porphyrin Supramolecules
    Satake, A.; Yamamura, M.; Oda, M.; Kobuke, Y. J. Am. Chem. Soc. 2008, 130, 6314-6315.
    
    
17. Recent Advances in Two-photon Photodynamic Therapy
    Ogawa, K.; Kobuke, Y. Curr. Med. Chem. - Anti-Cancer Agents 2008, 8, 269-279.
    
    
18. Stepwise Elongation Effect on the Two-photon Absorption of Self-assembled Butadiyne Porphyrins
    Dy, J. T.; Ogawa, K.; Kamada, K.; Ohta, K; Kobuke, Y. Chem. Commun. 2008, 3411-3413.

2007


Original papers

1. Structure and Ligand Binding Properties of Myoglobins Reconstituted with Monodepropionated Heme: Functional Role of Each Heme-Propionate Side Chain
   Harada, K.; Makino, M.; Sugimoto, H.; Hirota, S.; Matsuo, T.; Shiro, Y.; Hisaeda, Y.; Hayashi, T. Biochemistry 2007, 46, 9406-9416.
   
   
2. Trapping of a Dopaquinone Intermediate in the TPQ Cofactor Biogenesis in a Copper-containing Amine Oxidase from Arthrobacter globiformis
   Moore, R. H.; Spies, M. A.; Culpepper, M. B.; Murakawa, T.; Hirota, S.; Okajima, T.; Tanizawa, K.; Mure, M. J. Am. Chem. Soc. 2007, 129, 11524-11534.
   
   
3. Thermodynamical Properties of Reaction Intermediates during Apoplastocyanin Folding in Time-Domain
   Baden, N.; Hirota, S.; Takabe, T.; Funasaki, N.; Terazima, M. J. Chem. Phys. 2007, 127, 175103 (12 pages).
   
   
4. A Photochromic Porphyrin-perinaphthothioindigo Conjugate and its Two-photon Absorption Properties
   Dy, J. T.; Maeda, R.; Nagatsuka, Y.; Ogawa, K.; Kamada, K.; Ohta, K.; Kobuke, Y.  Chem. Commun. 2007, 5170-5172.
   
   
5. Syntheses and Properties of Acetylene-linked Bis- and Trisporphyrins toward Two-photon Photodynamic Therapy
   Inaba, Y.; Ogawa, K.; Kobuke, Y. J. Porphyrins Phthalocyanines 2007, 11, 406-417.
   
   
6. Syntheses and Nonlinear Absorption Properties of Conjugated Porphyrin Supramolecules
   Ogawa, K.; Hara, C.; Kobuke, Y. J. Porphyrins Phthalocyanines 2007, 11, 359-367.
   
   
7. Ligand-Induced Interconversion of a Coordination-Organized Porphyrin Dimer: a Potential Fluorescence-based Molecular Memory Monitor,
   Satake, A.; Tanihara, J.; Kobuke, Y. Inorg. Chem. 2007, 46, 9700-9707.
   
   
8. Water-soluble Self-assembled Butadiyne-bridged Bisporphyrin: a Potential Two- Photon Absorbing Photosensitizer for Photodynamic Therapy
   Dy, J.; K. Ogawa, K.; Satake, A.; Ishizumi, A.; Kobuke, Y. Chem. Eur. J. 2007, 13, 3491-3500.
   
   
9. Singlet Oxygen Generation and Photocytotoxicity against Tumor Cell by Two-Photon Absorption
   Ogawa, K.; Dy, J.; Kobuke, Y.; Ogura, S.; Okura, I. Mol. Cryst. Liq. Cryst. 2007, 471, 61-67.
   
   
10. Supramolecular Array of Imizazolylethynyl-zinc-porphyrin,
    Satake, A.; Shoji, O.; Kobuke, Y. J. Organomet. Chem. 2007, 69, 635-644.
    
    
11. Heme Orientational Disorder in Human Adult Hemoglobin Reconstituted with a Ring Fluorinated Heme and Its Functional Consequences
    Nagao S.; Hirai Y.; Kawano S.; Imai K.; Suzuki A.; Yamamoto Y. Biochem. Biophys. Res. Commun. 2007, 354, 681-685.

Reviews (International achievements only)

1. Assemblies of Porphyrins and Phthalocyanines Showing Strong Electronic　Coupling
   Satake A.; Kobuke, Y. Organic and Bioorganic Chemistry,2007, 5, 1679-1691.
   
   
2. Supramolecular Porphyrin Systems by Self-organization for Nano-photonic Device
   Kobuke, Y.; Satake, A.; Ogawa, K. in BOTTOM-UP NANOFABRICATION: Supramolecules, Self-Assemblies, and Organized Films, 2007, Chapter 16, 1-27.

2006


Original papers

1. Chemical Shifts as a Novel Measure of Interactions between Two Binding Sites of Symmetric Dialkyldimethylammonium Bromides to α-Cyclodextrin
   Funasaki, N.; Ishikawa, S.; Hirota, S. Anal. Chim. Acta 2006, 555, 278-285.
   
   
2. "Click Peptide" Based on the "O-Acyl Isopeptide Method": Control of Aβ1-42 Production from a Photo-Triggered Aβ1-42 Analogue
   Taniguchi, A.; Sohma, Y.; Kimura, M.; Okada, T.; Ikeda, K.; Hayashi, Y.; Kimura, T.; Hirota, S.; Matsuzaki, K.; Kiso, Y. J. Am. Chem. Soc. 2006, 128, 696-697.
   
   
3. Molecular Motions of α-Cyclodextrin on a Dodecyl Chain Studied by Molecular Dynamics Simulations
   Ishikawa, S.; Hirota, S.; Neya, S.; Funasaki, N. Chem. Pharm. Bull. 2006, 54, 528-534.
   
   
4. Kinetic and Structural Studies on the Catalytic Role of the Aspartic Acid Residue Conserved in Copper Amine Oxidase
   Chiu, Y.-C.; Okajima, T.; Murakawa, T.; Uchida, M.; Taki, M.; Hirota, S.; Kim, M.; Yamaguchi, H.; Kawano, Y.; Kamiya, N.; Kuroda, S.; Hayashi, H.; Yamamoto, Y.; Tanizawa, K. Biochemistry 2006, 45, 4105-4120.
   
   
5. Iron Porphyrin-Cyclodextrin Supramolecular Complex as a Functional Model of Myoglobin in Aqueous Solution
   Kano, K.; Kitagishi, H.; Dagallier, C.; Kodera, M.; Matsuo, T.; Hayashi, T.; Hisaeda, Y.; Hirota, S. Inorg. Chem. 2006, 45, 4448-4460.
   
   
6. Micelle Formation of Bile Salts and Zwitterionic Derivative as Studied by Two-Dimensional NMR Spectroscopy
   Funasaki, N.; Fukuba, M.; Hattori, T.; Ishikawa, S.; Okuno, T.; Hirota S. Chem. Phys. Lipids 2006, 142, 43-57.
   
   
7. Conformational Changes during Apoplastocyanin Folding Observed by Photocleavable Modification and Transient Grating
   Hirota, S.; Fujimoto, Y.; Choi, J.; Baden, N.; Katagiri, N.; Akiyama, M.; Hulsker, R.; Ubbink, M.; Okajima, T.; Takabe, T.; Funasaki, N.; Watanabe, Y.; Terazima, M. J. Am. Chem. Soc. 2006, 128, 7551-7558.
   
   
8. Development of First Photoresponsive Prodrug of Paclitaxel
   Skwarczynski, M.; Noguchi, M.; Hirota, S.; Sohma, Y.; Kimura, T.; Hayashi, Y.; Kiso, Y. Bioorg. Med. Chem. Lett. 2006, 16, 4492-4496.
   
   
9. Masking Mechanisms of Bitter Taste of Drugs Studied with Ion Selective Electrodes
   Funasaki, N.; Uratsuji, I.; Okuno, T.; Hirota, S.; Neya, S. Chem. Pharm. Bull. 2006, 54, 1155-1161.
   
   
10. A Myoglobin Functional Model Composed of a Ferrous Porphyrin and a Cyclodextrin Dimer with an Imidazole Linker
    Kano, K.; Kitagishi, H.; Mabuchi, T.; Kodera, M.; Hirota, S. Chem. Asian J. 2006, 1, 358-366.
    
    
11. Reduction of Plastocyanin by Tyrosine-Containing Oligopeptides
    Hirota, S.; Okumura, H.; Kondoh, T.; Funasaki, N.; Takabe, T.; Watanabe, Y. J. Inorg. Biochem. 2006, 100, 1871-1878.
    
    
12. 'Click peptide’: a novel ‘O-acyl isopeptide method’ for peptide synthesis and chemical biology-oriented synthesis of amyloid βpeptide analoguesShoma, Y.; Taniguchi, A.; Yoshiya, T.; Chiyomori, Y.; Fukao, F.; Nakamura, S.; Skwarczynski, M.; Okada, T.; Ikeda, K.; Hayashi, Y.; Kimura, T.; Hirota, S.; Matsuzaki, K.; Kiso, Y. J. Pept. Sci. 2006, 12, 823–828.
    
    
13. Direct Observation of Photoinduced Electron Transfer in Zinc Porphyrin / Zinc Phthalocyanine Composite
    Ito, F.; Ishibashi, Y.; Khan, S. R.; Miyasaka, H.; Kameyama, K.; Morisue, M.; Satake, A.; Ogawa, K.; Kobuke, Y. J. Phys. Chem. A 2006, 110, 12734-12742.
    
    
14. Construction and Photophysical Properties of Self-assembled Linear Porphyrin Arrays
    Ogawa, K.; Kobuke, Y. J. Photochem. Photobiol. C 2006, 7, 1-16.
    
    
15. Single molecular observation of penta- and hexagonic assembly of bisporphyrin on a gold surface
    Satake, A.; Tanaka, H.; Hajjaj, F.; Kawai, T.; Kobuke, Y. Chem. Commun. 2006, 2542-2544.
    
    
16. A Supramolecular Photosynthetic Triad of Slipped Cofacial Porphyrin Dimer, Ferrocene, and Fullerene
    Nakagawa, H.; Ogawa, K.; Satake, A.; Kobuke, Y. Chem. Commun. 2006, 1560-1562.
    
    
17. Assemblies of Supramolecular Porphyrin Dimers in Pentagonal and Hexagonal Arrays Exhibiting Light-Harvesting Antenna Function
    Hajjaj, F.; Yoon, Z. S.; Yoon, M.-C.; Park, J.; Satake, A.; Kim, D.; Kobuke, Y. J. Am. Chem. Soc. 2006, 128, 4612-4623.
    
    
18. Water-Soluble Bis(imidazolylporphyrin) Self-Assemblies with Large Two-Photon Absorption Cross Sections as Potential Agents for Photodynamic Therapy
    Ogawa, K.; Hasegawa, H.; Inaba, Y.; Kobuke, Y.; Inouye, H.; Kanemitsu, Y.; Kohno, E.; Hirano, T.; Ogura, S.; Okura, I. J. Med. Chem. 2006, 49, 2276-2283.
    
    
19. Two-photon Absorption Properties of Conjugated Supramolecular Porphyrins with Electron Donor and Acceptor
    Tanihara, J.; Ogawa, K.; Kobuke, Y. J. Photochem. Photobiol. A 2006, 178, 140-149.
    
    
20. Synthesis of Hexazincporphyrin and Hexaamine Substituted Ru(bipy)3 Complexes for Alternate Self-Assembly by Tritopic Coordinations
    Fukuda, S.; Satake, A.; Kobuke, Y. Thin Solid Films 2006, 499, 263-268.

Review (International achievements only)

1. ¹⁹F NMR Study of b-Type Haemoproteins
   Yamamoto Y; Nagao S.; Suzuki A. Modern Magnetic Resonance, Webb, G. A. Ed., Springer, 2006, pp.527-534.