Research in 2022(Jump to RECREATION)

...Mr. Odani stayed in Taiwan National Yang Ming University for Short-term research program

Mr. Odani joined the Short-term research program of Taiwan National Yang Ming University. He did experiments in Prof. Fu-jen Kao's Laboratory.With using light source and camera, he work on the theme for detection of blood condition.

...A science show for kids named"Laboratory Tour 2022 in NAIST, Let's learn the mysterious relationship between color and light!" was held.

Prof. Hosokawa gave a lecture at the webinar, and Prof. Yaxaier gave a tour of the research facilities and then answered questions from the participants with our master students. In the experiment section, we observed waveforms of various colored papers and fallen leaves with a spectrometer, and enjoyed an experiment show by Mr. Kumo M from Science Kido. About 60 kids and parents enjoyed the event.

Event information by Watson Co., Ltd.→here.



...Prof.Hosokawa gave a special lecture at Osaka University.

Prof.Hosokawa gave a special lecture at the 10th Graduate Seminar of Applied Physics Course Graduate School, Department of Physics, Osaka University, where he graduated.

Prof. Hosokawa フェムト秒レーザーが生体物質に及ぼす強励起現象を駆使した細胞の操作と計測

...Papers about AI-Enabled Microfluidic Devices are Published in Sensors and Actuators B: Chemical, ACS Sensors.

We published a paper on the development of an "AI-equipped microfluidic device" as a device that can measure, analyze, and determine the resistance and sensitivity of microorganisms such as E. coli to drugs quickly and automatically with high accuracy using a technique called electrical (impedance) measurement that examines the electrical characteristics of cells.
The article "Real-time recognition system for antibiotic-sensitive bacteria by parallel cytometry using machine learning" has been published in Sensors and Actuators B: Chemical. DOI: 10.1016/j.snb.2022.132698
Real-time screening of bacterial single cells from nano to micro scale by parallel impedance cytometry" was published in "ACS Sensors".DOI: 10.1021/acssensors.2c01351

University press release on this article

...New special student came

New special student joined our lab.



Ma Doudou
Hello everyone, my name is Ma Doudou and I come from China. My hobby is playing billiards and my area of expertise is microfluidics.

...Degree-granting

The degree conferment ceremony was held. Three students from our laboratory,
who are D3 Dr. Tang, Dr. Dian and M2 Mr. Priyo received their degrees in our laboratory.

... Joined The 4th Young People's Association on Plant structure opt 2022

We joined The 4th Young People's Association on Plant structure opt 2022 in Elucidation of the strategies of mechanical optimization in plants toward the establishment of the bases for sustainable structure system. D1 Mr. Yamasaki, M2 Mr.Priyo, Mr.Murakishi participated.



講演内容
Y.Yamasaki フェムト秒レーザー加工と原子間力顕微鏡計測による植物細胞の力学状態評価
R.Priyo Photoinjection of DNA plasmids into intact Tobacco BY-2 cells
T.Murakishi フェムト秒レーザー誘起衝撃力に誘導される培養細胞組織の振動挙動の原子間力顕微鏡による検出


...Joined the 83th JSAP Fall Meeting 2022

Dr. Tanga, Dr. Tsuri, D3 Mr.Yi, M2 Mr.Akao, Mr.Inoue, Ms.Onishi and Mr.Odani participated in the 69th JSAP Spring Meeting 2022.


講演内容
N.Tanga フェムト秒レーザーフォトポレーションによる正常動物 細胞への遺伝子導入
Y. Tsuri アントラセンのレーザー誘起結晶化における濃度勾配の 高速度観測
Y. Powei AFM Detection of Vibration Propagation in a Protein Microcrystal Triggered by Femtosecond Laser Impulse
H. Akao フェムト秒レーザー誘起衝撃力を用いたナノ粒子分取の ためのマイクロ流体チップ開発2:分取性能向上のため の流路形状の最適化
K. Inoue "レーザー加振した細胞シートの振動挙動の解析2 : AFM カンチレバーのレーザー加工による検出感度の最適化
R. Onishi 光散乱スペクトル測定による細胞内構造の評価
K. Odani フェムト秒レーザーを用いた力学刺激に対する細胞クラ スターのカルシウム応答解析


...Master's thesis presentation

M2 Mr. Priyo presented his master's thesis.


講演内容
R.Priyo Photinjection of DNA plasmids into Tobacco BY-2 cells utillizing femtosecond laser

....A paper was published in Scientific Reports

Our lab members and the team of researchers refine the equations for mechanical stiffness to apply to plant cell walls based on elastic shell theory and verified using finite element simulations, which may lead to a better understanding of how plants resist stress.

The letter in Scientific Reports is→
Elastic shell theory for plant cell wall stiffness reveals contributions of cell wall elasticity and turgor pressure in AFM measurement
https://doi.org/10.1038/s41598-022-16880-2

NAIST article is→Here

...PhD defense

The defense of has been held on 20-27 July, 2022.

Title
T. Tao FPGA-based system development for high-throughput single-cell detection and sorting from micro to nanoscale (FPGAシステム開発に基づいたハイスループット・マルチスケールな細胞計測と分取)
D. Anggraini Guidance of axon outgrowth activated by femtosecond laser processing in a microfluidic device (マイクロデバイスのフェムト秒レーザー加工によって制御された神経細胞の軸索伸長誘導)
Defense_tangtao.png Dian_defence.png

...Fellow joined the 2022 1st lecture of JSAP Kansai Chapter.

Dr. Tsuri (JSPS Postdoctoral Fellow) gave poster presentation at 2022 1st lecture of The Japan Society of Applied Physics Kansai Chapter.

Title
Y.Tsuri 短パルスレーザー照射によるアントラセンの結晶化における濃度場の高速度観測

...New master students came

6 new master students joined our lab.



Reo Namura
I'm from Aichi prefecture. My hobbies are watching anime, playing games, and reading books. My desire is to go to bed early, work hard for job hunting, and make money.
Thank you.

Ayuka Hatta
I'm from Kagawa prefecture. My hobby is visiting cat cafes.Thank you.

Yuki Maeda
I'm Yuki Maeda from Kobe City College of Technology. At that time, I was doing research on light. My hobbies are sports in general, especially baseball and golf. I will do my best without forgetting my original intention.Thank you.

Gaishi Murakami
I'm from Suita City, Osaka Prefecture. I like hot springs and radio. I want to improve my living ability by living in a dormitory.Thank you.

Rintaro Yoshinaga
I'm from Tokyo. I like sports (especially tennis). Thank you.

Yoshitaka Wakayama
I'm from Gifu prefecture. I'm from Keio University.My hobbies are listening to music and going to karaoke.My aspiration is to enjoy my research. Thank you.

...We gave poster presentation at COLA2021/2022

Prof. Hosokawa, Dr. Tsuri and Mr. Yamasaki gave poster presentations at 16th International Conference on Laser Ablation (COLA2022) that held in Shimane.  

Title
Y.Hosokawa Vibration behavior of AFM cantilever induced by the femtosecond laser impulse in the water
Y.Yamasaki Femtosecond laser perforation of plant cells for evaluation of cell stiffness

... JSPS Postdoctoral Fellow comes our lab

Dr. Tsuri comes our lab as a JSPS Postdoctoral Fellow.


Yuka Tsuri
My name is Yuka Tsuri. In April 2022, I joined this laboratory as a research fellow (PD) from JSPS. I studied crystallization control of organic compounds and crystallization dynamics, and got my Ph.D. in Division of Electrical, Electronic and Infocommunications Engineering at Osaka Univ. at March 2022. Here, I would like to develop a laser system to freely realize crystallization control in cooperation with lab members. Thank you.

...Chinese student came to our lab


劉洵 Liu Xun
My name is Liu Xun , written as 劉洵(りゅう しゅん). I come from China. I got my master's and bachelor's degrees from the Chinese Academy of Science and Jilin University, respectively. My hobby is cooking, trying various recipes on my way. My current research is on "microfluidic chips with ultra-high velocity and throughput." In addition, FEM simulations of optics, electricity, and mechanism are also in my interests.
We optimized the structure of connections and minimized the microchannel only for minified flow resistance in the microfluidic chip. By our microfluidic chip, a velocity of 40 m/s could be achieved by typical syringe pμmps. Utilizing optical time-stretch (OTS) microscopy, a ultra-high throughput of 2,700,000 cells/s could be reached at 15 m/s.

...joined The Institute of Electrical Engineers of Japan

M2 Mr.Yamasaki, Mr.Priyo and M1 Mr.Inoue participated in the Institute of Electrical Engineers of Japan held on both face-to-face and online



講演内容
Y.Yamasaki フェムト秒レーザー加工と原子間力顕微鏡計測による植物細胞の力学状態評価
R.Priyo Photoinjection of DNA plasmids into intact Tobacco BY-2 cells
K.Inoue フェムト秒レーザー誘起衝撃力に誘導される培養細胞組織の振動挙動の原子間力顕微鏡による検出


...Degree-granting

The degree conferment ceremony was held. Seven students from our laboratory, who are D3 Mr. Hao, M2 Mr. Iriguchi, Ms. Uno, Mr. Kiya, Mr. Takao, Mr. Hironaga and Mr. Yamasaki received their degrees in our laboratory.

...joined the 69th JSAP Spring Meeting 2022

M1 Mr. Akao, Mr. Inoue, Mr. Onishi, Mr. Odani and Mr. Murakishi participated in the 69th JSAP Spring Meeting 2022 held online.


講演内容
H. Akao フェムト秒レーザー誘起衝撃力を用いたナノ粒子分取のためのマイクロ流体チップ開発
K. Inoue レーザー加振した細胞シートの振動挙動の解析:振動検出のためのAFMカンチレバーの長さ依存性
R. Onishi 光散乱スペクトル測定による単一腫瘍細胞の悪性度評価
K. Odani フェムト秒レーザーに誘起される異なる力学作用に対する細胞のCa2+応答
T. Murakishi シャジクモが有する巨大細胞を用いたAFM力学計測による細胞壁の弾性率分析


...Master's thesis presentation

M2 Mr. Iriguchi, Ms. Uno, Mr. Kiya, Mr. Hironaga, Mr. Takao and Mr. Yamasaki presented their master's thesis.



講演内容
T.Iriguchi シャジクモにおけるAFM弾性率測定による植物細胞の構造に由来する力学特性評価
H.Uno 力学刺激に対する細胞のCa2+シグナル伝達応答に関わる細胞の力学的・生理学的パラメーターの探索
R.Kiya フェムト秒レーザー誘起衝撃力を用いた3択型細胞分取システムの開発
K.Hironaga フェムト秒レーザー誘起衝撃力を用いたゼブラフィッシュの胚発生を駆動する機械的な力の制御機構の探索
K.Takao フェムト秒レーザー誘起衝撃力によって加振された細胞組織の振動挙動の評価
Y.Yamasaki フェムト秒レーザー穿孔と原子間力顕微鏡法による植物細胞の力学状態評価

...Doctor's thesis presentation

D3 Hao presented their doctor's thesis.

講演内容
Hao Yansheng Development of Ultra-thin Glass Flow Velocity Sensor Fabricated by Femtosecond Laser Processing

...Interview videos has been released.

Professor Hosokawa was interviewed from a web channel called "Science Talks", and a youtube video has been released.

This video is full of the charms of Professor Hosokawa, so please take a look.

前編:世界一ありとあらゆる生きものにフェムト秒レーザーを当てた研究者


後編:ミドリムシであの人気キャラクターを描く!?レーザー技術の最先端!

Recreation in 2022 (Jump to RESEARCH

...We attended the wedding ceremony of Mr. and Mrs. Yamasaki

The wedding and reception of Mr. Yuki Yamasaki, a D1 student of our laboratory, and Mrs. Saki Yamasaki, an administrative assistant, was held in Yokohama.

Faculty members, staffs and alumni attended the ceremony both onsite and online, and Professor Hosokawa gave a congratulatory speech as a guest greeting. In his congratulatory speech, he introduced Mr. Yuki Yamasaki's research theme, and encouraged the couple to support each other's life, using the mechanical state of plant cells, which are supported by the balance between cell walls and internal pressure, as an analogy.

I was happy to hear that the alumni I met for the first time in several months were also doing well in their working lives.

The day was blessed with beautiful weather, and the ceremony was glorious, sunny, and wonderful... Congratulations!